Blastocyst culture is an advanced laboratory technique used during in vitro fertilization (IVF) to grow embryos for an extended period before implantation. This method involves cultivating embryos in a specialized incubator until they reach the blastocyst stage, which typically occurs around day 5 or day 6 after fertilization.
Blastocyst culture offers several advantages over traditional embryo culture methods, including improved embryo selection, higher implantation rates, and reduced risk of multiple pregnancies.
Following egg retrieval in the IVF laboratory, either through conventional IVF or ICSI, embryos undergo a meticulously controlled culture process. This involves sequential development stages:
Egg retrieval marks the beginning of the process.
The pronuclear stage, assessing fertilization success.
Embryos progress to the two to four cell stage.
Further development to the eight-cell stage.
Embryos reach the morula stage.
Culmination in the blastocyst stage, characterized by distinct inner cell mass and trophectoderm layers.
Extended culture allows for natural selection, enabling embryologists to identify the most viable embryos for transfer.
Aligning with natural pregnancy timelines, blastocyst transfer optimizes uterine receptivity, potentially improving implantation rates.
Facilitates pre-implantation genetic screening (PGS) or diagnosis (PGD), crucial for couples with genetic concerns.
By selecting the single best embryo for transfer, blastocyst culture reduces the risk of multiple pregnancies, ensuring safer outcomes.
Our esteemed IVF doctor in Lucknow brings over two decades of IVF expertise and experience. With a rich history of 22+ years, our dedicated fertility specialist in Lucknow is committed to making your parenthood dreams come true.
Our team comprises skilled fertility specialists, embryologists, and support staff with a proven track record of successful IVF procedures.
We boast modern, well-equipped facilities that adhere to the highest standards in reproductive medicine.
We give individualized care to our patient, with a customized treatment plan made for their specific needs.
We take pride in our high success rates, helping numerous couples start their journey of parenthood.
Our team provides emotional, psychological, and educational support throughout the entire IVF journey.
Blastocyst culture is particularly beneficial for:
MBBS, MD – Obstetrics & Gynecology
Dr. Neelam Mishra is a highly qualified medical professional with an extensive background in obstetrics and gynaecology. She completed her MBBS and MD in Obstetrics and Gynecology from the prestigious University College of Medical Sciences, located in Shahadra, New Delhi. With a solid foundation in medical education and training, Dr. Mishra further honed her expertise by specialising in infertility and embryology.
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The procedure starts with the consultation followed by blood tests, semen analysis, ovary stimulation, regular monitoring, trigger injection, egg collection, IVF, blastocyst, genetic test, grading, blastocyst transfer, and at last cryopreserved.
Yes, blastocysts can be frozen for future use. The common freezing technique is Vitrification which provides high survival rates upon thawing.
There is one risk that not all embryos will develop to the blastocyst stage, which could result in fewer embryos available for transfer.
Generally, the cost ranges from Rs 1.5 lakh to 2 lakhs. It depends on different factors like clinics, the condition of a person and other factors.
After fertilization in the laboratory, embryos are cultured for several days until they reach the blastocyst stage. A healthy blastocyst is then selected and transferred into the uterus using a thin catheter.
Factors such as the woman’s age, embryo quality, and previous IVF outcomes play a role in determining the best approach.
Blastocysts are more developed and have a higher chance of successful implantation compared to three-day-old embryos. By waiting until the blastocyst stage, the chances of pregnancy are increased.
